![]() ![]() ![]() We formulate capture efficiency as a novel parameter that can be used to better evaluations of specificity and coverage depth among the different capture platforms. The purpose of this study is to help investigators and clinicians select the appropriate platform for their particular application and lay the foundation for the development of a better target capture platform for next-generation sequencing. Here we compare the performance of the four platforms with different bait types to find out their advantages and limitations. Several different platforms for library preparation and target capture with different bait types respectively are commercially available. ![]() Next-generation sequencing technology is developing rapidly and target capture sequencing has become an important technique.
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